Please refer to the summary of the incident and the preliminary root cause provided by Microsoft on their incident history page:
https://status.azure.com/en-us/status/history/
They have also indicated that a full Post Incident Report will be posted within 72 hours.
Summary of Impact to Frame Customers: Between approximately 21:25 UTC on Sep 28 2020 and 00:23 UTC on Sep 29 2020, a subset of customers using services in the Azure Public and Azure Government clouds may have encountered errors performing operations for a number of Microsoft or Azure services. For Frame customers using Azure AD for user authentication, this meant that some users may not have been able to login and access applications and desktops. For a subset of customers using Azure infrastructure to host Frame workload VMs, operations which require authentication such as provisioning and starting VMs may have been impacted. The Frame platform automatically handled these Azure error conditions and retried affected operations until Azure services recovered. No manual intervention was required by Nutanix Frame operations teams to recover affected customers once Azure services recovered.